INFLAMMATORY BOWEL

DISEASE

At MagIC, we study the increasing occurrence of inflammatory bowel diseases like Crohn’s disease (CD) and ulcerative colitis (UC), particularly in developing regions.

 

Asian populations have different genetic tendencies towards IBD compared to Western populations. These genetic factors are not obligatory for IBD development; instead, environmental factors play a more significant role. Various factors in childhood, including travel exposure, diet, early antibiotic use, socio-economic status, and rural or urban upbringing, can impact the microbiome significantly.

 

Research shows that gut microbes play a crucial role in the development of these diseases. Additionally, geographic, dietary, and ethnic factors influence microbial diversity, affecting the progression and symptoms of IBD.